If you're interested learning Blender take a look at this site, I found it very easy and helpful:
http://www.gryllus.net/Blender/3D.html .
For me Blender is a great application! I mean, not as easy to grasp as Hexagon, but much more powerful (and I am thinking only about modelling, voluntarily omitting that Blender has also good rendering features).
The interface not so bad: you can divide your screen in as many viewport as you want, and assign a specific function to each viewport (3D view, ortographic view, buttons panel, object list, etc.).
When a viewport cannot display all the information (typical is for button ones) you simply scroll with mouse wheel to show hidden content.
Not a big deal, you have to learn where are the commands you want, but isn't it true with any application?
The biggest limit I can see is that keystrokes are fixed, not configurable, and sometimes they are not so intuitive.
Some examples: Tab switch between Object mode and Edit mode; Shift+Tab switch snapping on/off; Ctrl+Tab brings up selection mode (vert-edge-face); W brings up "common used" menu... etc.
You don't even need to memorize shortcuts because they are written nearby every menu command, and you have menus and buttons for each and every function.
Wrap up: Blender is well worth a try, but if you don't think to try seriously don't even begin because you'll get only confusion.
That's my two cents, peace and love to everybody. :-)