I have tried Blender a number of times. Can't get along with it - relies too much on a mouse with middle mouse button (I use a tablet and pen) and uses some strange conventions that I don't have time to learn.
It's a shame as it appears to be a capable 3D tool. But, as is often the case, the interface and interaction are the last things to be considered.
As a contrast I've been looking at MoI and Modo. Both of these apps have interfaces that I can easily get around leaving me free to learn the tool and then get creating.
My tuppence worth

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